It is well known that common variants in specific genes influence drug metabolism and response, but it is currently unknown what fraction of patients are given prescriptions over a lifetime that could be contraindicated by their pharmacogenomic profiles.To determine the clinical utility of pharmacogenomics over a lifetime in a general Appliance Pac
Here, we describe a sorbitol-based optical clearing method, called modified Sca/eS that can be used to image all hair cells (HCs) in the mouse cochlea.This modification of Sca/eS is defined by three steps: decalcification, de-lipidation, and refractive index matching, which can all be completed within 72 h.Furthermore, we established automated anal
Abstract Objectives Neural networks are a powerful statistical tool that use nonlinear regression type models to obtain predictions.Their use in the Lifeways cross-generation study that examined body mass index (BMI) of children, among other measures, is explored here.Our aim is to predict the BMI of children from that of their parents and maternal
A community outbreak of human influenza A(H1N1)pdm09 virus strains was observed in Myanmar in 2017.We investigated the DANDRUFF/DRY SCALP SHAMPOO circulation patterns, antigenicity, and drug resistance of 2017 influenza A(H1N1)pdm09 viruses from Myanmar and characterized the full genome of influenza virus strains in Myanmar from in-patients and out
During the last century, most philosophers of science have tried to expunge teleological explanations from the fields of epistemology.They took for granted that the Darwinian concepts of natural selection Bouncy Ball and evolution effectively dispense us with any presence of goal-directedness in nature: based on an anti-metaphysical attitude, they